I have been suffering from paralyzing depressions. Sometimes I seriously ask myself how someone can feel this bad and live. Often I simply collapse in ed. I mean bed, of course… come to think of it, never had a lover named Ed. This is not some superattenuated, arcane, exclusive depression known only to the chosen and distinguished few. It is a realization of the raw horror of the human position at this point.
— Burroughs, My Education: A Book of Dreams